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For adults with chronic kidney disease (CKD), FARXIGA is a prescription medicine approved to reduce the risk of further worsening of kidney disease, end-stage kidney disease, death due to cardiovascular disease, and hospitalization for heart failure.

Check your Kidney Numbers
Check your Kidney Numbers

CHRONIC KIDNEY DISEASE

What's on the horizon for your kidneys? Check your kidney numbers to find out

Understanding your lab work

With CKD, loss of kidney function happens gradually and can rarely be recovered. So, checking your kidney numbers on your lab work is important. It’s a great way to find out how well your kidneys are doing their job. Kidney numbers come from 2 tests: eGFR* and UACR.†

*eGFR stands for “estimated glomerular filtration rate.” eGFR is measured in mL/min/1.73 m2.
†UACR stands for “urine albumin-to-creatinine ratio.” UACR is measured in mg/g.

eGFR Kidney Number
eGFR Kidney Number

One kidney number to check: eGFR


What is eGFR?

eGFR tests measure your level of kidney function—from normal kidney function to kidney failure. An eGFR of less than 60 for 3 or more months may mean you have CKD. eGFR is measured in mL/min/1.73 m2.

Your eGFR is easy for your doctor to track. It's a blood test included in most comprehensive blood panels done for routine physicals.
 

Select a tab to learn more about eGFR and the stages of CKD.

Stage 1 CKD - Minimal Kidney Damage
Stage 1 CKD - Minimal Kidney Damage

Stage 1: Minimal kidney damage with normal kidney function


How you may feel:

You may not have symptoms. CKD is called a “silent disease” because most people don’t feel symptoms in the early stages.

Stage 2 CKD - Mild Loss of Kidney Function
Stage 2 CKD - Mild Loss of Kidney Function

Stage 2: Kidney damage with mild loss of kidney function

 

How you may feel:

In this stage, you still may not know you have CKD. That’s because early on, most people don’t feel symptoms.

Stage 3 CKD - Mild to Moderate or Severe Loss of Kidney Function
Stage 3 CKD - Mild to Moderate or Severe Loss of Kidney Function

This stage is broken up into 2 parts.

STAGE 3a (45-59): Mild to moderate loss of kidney function

STAGE 3b (30-44): Moderate to severe loss of kidney function

 

How you may feel:

You could feel tired and weak or notice some swelling in your hands or feet.

Stage 4 CKD - Severe Loss of Kidney Function
Stage 4 CKD - Severe Loss of Kidney Function

Stage 4: Severe loss of kidney function

 

How you may feel:

You might feel tired and weak or notice you’re not as hungry. You could also have some discomfort in your lower back or have swelling in your hands or feet.

Stage 5 CKD - Kidney Failure Requires Dialysis or Transplant
Stage 5 CKD - Kidney Failure Requires Dialysis or Transplant

Stage 5: Kidney failure, which may require dialysis or transplant

 

How you may feel:

You may feel very sick at this stage. That’s because your kidneys are either about to stop working or already have stopped working. This means they aren’t filtering waste out of your blood anymore and waste products are building up in your body.

UACR
UACR

The other kidney number to check: UACR

UACR tests show if you have increased protein in your pee. If your UACR is 30 or more for 3 or more months, it could mean there's kidney damage and may mean you have CKD. UACR is measured in mg/g.
 

Talk to your doctor if you notice changes in how often you pee or what your pee looks like.
 

What do UACR numbers tell you?

Below 30 - Normal To Mildly Increased protein Level

Normal to mildly increased protein level

30-300 - Moderately Increased protein Level

Moderately increased protein level

Above 300 - Severely Increased protein Level

Severely
increased protein level

Number 2 Cause of CKD is High Blood Pressure

Severely increased
protein level

Taking care of your kidneys can start today

ways to protect kidneys

FARXIGA is proven to help:

 

 

  • Reduce Risk of Kidney Failure

    Reduce the risk of
    kidney failure, which
    can lead to dialysis

  • Slow Progression of CKD

    Slow the
    progression
    of CKD

  • Reduce the Risk of Cardiovascular Death

    Keep you living life by
    reducing the risk of
    cardiovascular death

FARXIGA Savings Card
FARXIGA Savings Card

Pay $0* a month for Brand-Name FARXIGA

DOWNLOAD SAVINGS CARD

Subject to eligibility and monthly savings limit. Restrictions apply.

*Eligible commercially insured patients can get Brand-Name FARXIGA for as low as $0 as long as their doctor prescribes it. Not available for government-insured patients.

IMPORTANT SAFETY INFORMATION

Who should not take FARXIGA?

Do not take FARXIGA if you are allergic to dapagliflozin or any of the ingredients in FARXIGA. Symptoms of a serious allergic reaction may include skin rash, raised red patches on your skin (hives), swelling of the face, lips, tongue, and throat that may cause difficulty in breathing or swallowing. If you have any of these symptoms, stop taking FARXIGA and contact your healthcare provider or go to the nearest hospital emergency room right away.

What are the possible side effects of FARXIGA?

FARXIGA may cause serious side effects including:

  • Ketoacidosis. FARXIGA can cause ketoacidosis, a serious condition which may require hospitalization and lead to death. People with type 1 diabetes, type 2 diabetes, or pancreas problems have a high risk of getting ketoacidosis. Signs and symptoms may include nausea, tiredness, vomiting, trouble breathing, abdominal pain, and ketones in your urine or blood. If you get any of these symptoms, stop taking FARXIGA and call your healthcare provider right away. If possible, check for ketones in your urine or blood, even if your blood sugar is less than 250 mg/dL
  • Dehydration (the loss of body water and salt), which may cause you to feel dizzy, faint, lightheaded, or weak, especially when you stand up (orthostatic hypotension). There have been reports of sudden kidney injury in people with type 2 diabetes who are taking FARXIGA. You may be at a higher risk of dehydration if you take medicines to lower your blood pressure, including water pills (diuretics); are age 65 or older; are on a low salt diet, or have kidney problems. Talk to your healthcare provider about what you can do to prevent dehydration including how much fluid you should drink on a daily basis. Call your healthcare provider right away if you reduce the amount of food or liquid you drink, or if you experience vomiting or diarrhea
  • Genital and urinary tract infections. FARXIGA can cause serious infections in your genital area or urinary tract that could require hospitalization. A rare but serious bacterial infection called necrotizing fasciitis can cause damage to the tissue under the skin in the area between and around the anus and genitals (perineum). This infection may require hospitalization, multiple surgeries, and could lead to death. Seek medical attention immediately if you have a fever or you are feeling very weak, tired or uncomfortable (malaise), and you develop pain or tenderness, swelling, or redness of skin (erythema) in the area between and around your anus and genitalsAlso tell your healthcare provider if you have any of these signs or symptoms of infection:
    • urinary tract infection: burning feeling when you urinate, need to urinate often or right away, pain in the lower part of your stomach (pelvis), blood in your urine. You may also have a fever, back pain, nausea, or vomiting
    • vaginal yeast infection: vaginal odor, white or yellowish vaginal discharge (may be lumpy or look like cottage cheese), vaginal itching
    • yeast infection of the skin around the penis: swelling of an uncircumcised penis may make it difficult to pull back the skin around the tip of your penis. Other symptoms include: redness, itching, or swelling of the penis, bad smelling discharge from the penis, rash on the penis, and/or pain in the skin around the penis. Talk to your healthcare provider about what to do if you get symptoms of a yeast infection. They may suggest you use an over-the-counter antifungal medicine. Contact your healthcare provider right away if your symptoms do not improve after using an over-the-counter antifungal medicine
  • Low blood sugar (hypoglycemia) can occur if you take FARXIGA with another medicine that can cause low blood sugar, such as sulfonylureas or insulin. Symptoms of low blood sugar include shaking, sweating, fast heartbeat, dizziness, hunger, headache, and irritability. Follow your healthcare provider's instructions for treating low blood sugar

The most common side effects of FARXIGA include yeast infections of the vagina or penis; stuffy or runny nose and sore throat; and changes in urination, including urgent need to urinate more often, in larger amounts, or at night.

What should I tell my healthcare provider before taking FARXIGA?

Before you take FARXIGA, tell your healthcare provider:

  • all of your medical conditions, including problems with your liver or pancreas
  • if you have had diabetic ketoacidosis
  • if you have type 1 diabetes, decrease in your insulin dose, serious infection, history of infection of the vagina or penis, history of urinary tract infections, or problems with urination
  • if you are on a low sodium diet, going to have surgery, eating less or change in diet, dehydrated, or binge drink
  • if you are pregnant, or plan to become pregnant. FARXIGA may harm your unborn baby
  • if you are breastfeeding, or plan to breastfeed. It is unknown if FARXIGA passes into your breast milk
  • about all the medicines you take, including prescription and nonprescription medicines, vitamins, and herbal supplements

APPROVED USES FOR FARXIGA

What is FARXIGA?

FARXIGA is a prescription medicine used to:

  • improve blood sugar control along with diet and exercise in adults and children who are 10 years of age and older with type 2 diabetes
  • reduce the risk of hospitalization for heart failure in adults with type 2 diabetes and known cardiovascular disease or multiple cardiovascular risk factors 
  • reduce the risk of cardiovascular death, hospitalization for heart failure, and urgent heart failure visit in adults with heart failure, when the heart cannot pump enough blood to the rest of your body 
  • reduce the risk of further worsening of your kidney disease, end-stage kidney disease, death due to cardiovascular disease, and hospitalization for heart failure in adults with chronic kidney disease 


FARXIGA is not for use to improve blood sugar (glucose) control in people with type 1 diabetes.

FARXIGA is not for use to improve blood sugar (glucose) control in people with type 2 diabetes who have moderate to severe kidney problems, because it may not work.

FARXIGA is not for people with certain genetic forms of polycystic kidney disease, or who are taking or have recently received immunosuppressive therapy to treat kidney disease. FARXIGA is not expected to work if you have these conditions.

Important Safety Information

WHAT HAPPENS WHEN YOU PROVIDE YOUR PERSONAL INFORMATION

AstraZeneca respects your personal health information. The information you provide may be used to send you health-related materials and to develop products, services, and programs. Third parties working on behalf of AstraZeneca may receive information that includes the date that you filled the prescription, the quantity of medication dispensed by your pharmacist, and your savings under the Program. AstraZeneca, or third parties working on our behalf, will not sell or rent personal health information. If in the future you no longer want to receive these materials, please call 1-844-798-3617.

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ELIGIBILITY AND TERMS OF USE

ELIGIBILITY: You may be eligible for this offer if you are insured by commercial insurance and your insurance does not cover the full cost of your prescription, or you are not insured and are responsible for the cost of your prescriptions. Patients who are enrolled in a state or federally funded prescription insurance program are not eligible for this offer. This includes patients enrolled in Medicare Part D, Medicaid, Medigap, Veterans Affairs (VA), Department of Defense (DOD) programs or TriCare, and patients who are Medicare eligible and enrolled in an employer-sponsored group waiver health plan or government-subsidized prescription drug benefit program for retirees. If you are enrolled in a state or federally funded prescription insurance program, you may not use this savings card even if you elect to be processed as an uninsured (cash-paying) patient. This offer is not insurance, is restricted to residents of the United States and Puerto Rico, and to patients over 18 years of age.

 

TERMS OF USE: Eligible commercially insured patients with a valid prescription for a FARXIGA® (dapagliflozin) Branded Family product who present this savings card at participating pharmacies will pay as low as $0 per 30-day supply subject to a maximum savings of $175 per 30-day supply. If you pay cash for your prescription, AstraZeneca will pay up to the first $150, and you will be responsible for any remaining balance, for each monthly prescription. Other restrictions may apply. Patient is responsible for applicable taxes, if any. Non-transferable, limited to one per person, cannot be combined with any other offer. Void where prohibited by law, taxed or restricted. Patients, pharmacists, and prescribers cannot seek reimbursement from health insurance or any third party for any part of the benefit received by the patient through this offer. AstraZeneca reserves the right to rescind, revoke, or amend this offer, eligibility and terms of use at any time without notice. This offer is not conditioned on any past, present or future purchase, including refills. Offer must be presented along with a valid prescription at the time of purchase. If you have any questions regarding this offer, please call 1-800-236-9933.

BY USING THIS CARD, YOU AND YOUR PHARMACIST UNDERSTAND AND AGREE TO COMPLY WITH THESE ELIGIBILITY REQUIREMENTS AND TERMS OF USE.